The first member of the group to be discovered is chlortetracycline aureomycin in the late 1940s by benjamin minge duggar, a scientist employed by american cyanamid – lederle laboratories, under the leadership of yellapragada subbarow, who derived the substance from a golden-colored, fungus-like, soil-dwelling bacterium named streptomyces aureofaciens.
Information about Tetracycline.
Take this medication on an empty stomachat least 1 hour before or 2 hours after meals.
All tetracyclines are about equally active and typically have about the same broad spectrumwhich comprises both aerobic and anaerobic gram-positive and gram-negative bacteriamycoplasmasrickettsiaechlamydiaeand even some protozoaamebaeTetracyclines generally are the drug of choice to treat rickettsiae and mycoplasmaAmong the susceptible organisms is Wolbachiaa rickettsial-like intracellular endosymbiont of nematodesincluding Dirofilaria immitisStrains of Pseudomonas aeruginosaProteusSerratiaKlebsiellaand Trueperella spp frequently are resistantas are many pathogenic Escherichia coli isolatesEven though there is general cross-resistance among tetracyclinesdoxycycline and minocycline usually are more effective against staphylococci.
There’s a lag period of one to three weeks between the change in dosage and its effect on skinIf the skin problem becomes worsereturn to the previous higher dosage and continue on it or as advised by your doctor.
Prevention of contamination of the environment with pig feces is importantReducing human contact with infected pigs and with contaminated food and water as well as improvement in conditions of personal hygiene and nutrition are additional methods of controlControl of cockroacheswhich are an important reservoir for cysts of Bcoliis important especially in areas where people use pit latrines24.
Before taking tetracyclinetell your doctor if you have liver or kidney diseaseYou may not be able to take tetracyclineor you may require a dosage adjustment or special monitoring during therapy.
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