During pre-marketing clinical trials, olanzapine-associated constipation, dry mouth, and tachycardia were reported, and are likely due to anticholinergic effects.
Information about Olanzapine.
Adverse Reactions Associated With Discontinuation Of Treatment In Short-Term Combination Trials.
Increased risk of hyperglycemia and diabetesin some caseshyperglycemia concomitant with use of atypical antipsychotics has been associated with ketoacidosishyperosmolar comaor death.
A potentially fatal symptom complex sometimes referred to as Neuroleptic Malignant SyndromeNMSreportedmanagement of NMS should include1immediate discontinuation of antipsychotic drugs and other drugs not essential to concurrent therapy2intensive symptomatic treatment and medical monitoringand 3treatment of any concomitant serious medical problems for which specific treatments are availablethere is no general agreement about specific pharmacological treatment regimens for NMSif patient requires antipsychotic drug treatment after recovery from NMSpotential reintroduction of drug therapy should be carefully consideredpatient should be carefully monitoredsince recurrences of NMS reported.
Use caution in patients at risk of pneumoniamay cause esophageal dysmotility and aspiration.
Adverse Reactions Associated With Discontinuation Of Treatment In Short-Term Combination Trials.
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