Consider hematology consultation before initiating or during clozaril treatment as necessary.
Information about Clozaril.
This medication may rarely cause a very serious condition called neuroleptic malignant syndromeNMSGet medical help right away if you have any of the following symptomsfevermuscle stiffness/pain/tenderness/weaknesssevere tirednesssevere confusionsweatingfast/irregular heartbeatdark urinesigns of kidney problemssuch as change in the amount of urine
Owing to its anti-alpha-adrenergic propertiesClozaril may reduce the blood-pressure-increasing effect of norepinephrine or other predominantly alpha-adrenergic agents and reverse the pressor effect of epinephrine.
Clozaril is also indicated in psychotic disorders occurring during the how much robaxin course of Parkinson’s diseasein cases where standard treatment has failed.
Continue Clozaril treatmentsample blood twice weekly until counts stabilise or increase.
Patients in whom Clozaril has been discontinued as a result of either WBC or ANC deficienciessee abovemust not be re-exposed to Clozaril.
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