Premarin equine contains a very large amount of this very potent form of estrogen which is one of many reasons why it should not be used.
Information about Premarin.
Estrogen administration may lead to severe hypercalcemia in women with breast cancer and bone metastasesIf hypercalcemia occursuse of the drug should be stopped and appropriate measures taken to reduce the serum calcium level.
The use of estrogen-alone and estrogen plus progestin therapy has been reported to result in an increase in abnormal mammogramsrequiring further evaluation.
There are no special dosage requirements for elderly patientsbut as with all medicinesthe lowest effective dose should be used.
When prescribing solely for the prevention of postmenopausal osteoporosistherapy should only be considered for women at significant risk of osteoporosis and non-estrogen medications should be carefully considered.
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