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Do not give this medicine to a child younger than 2 years old without the advice of a doctor.
Taking an NSAID can increase your risk of life-threatening heart or circulation problemsincluding heart attack or strokeThis risk will increase the longer you use an NSAIDDo not use this medicine just before or after having heart bypass surgeryalso called coronary artery bypass graftor CABG
Advise patients to stop Ponstel immediately if they develop any type of rash and contact their healthcare provider as soon as possiblesee WARNINGSSerious Skin Reactions
Inform patients of the signs of an anaphylactic reactione.gdifficulty breathingswelling of the face or throatInstruct patients to seek immediate emergency help if these occursee CONTRAINDICATIONSWARNINGSAnaphylactic Reactions
There is no consistent evidence that concurrent use of aspirin mitigates the increased risk of serious CV thrombotic events associated with NSAID useThe concurrent use of aspirin and an NSAIDsuch as mefenamic acidincreases the risk of serious gastrointestinalGIeventssee WARNINGSGastrointestinal BleedingUlcerationand Perforation
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