Probenecid benemid ; some nonsteroidal anti-inflammatory drugs nsaids ; aspirin or other salicylates including pepto-bismol ; sulfa drugs bactrim, gantanol, septra, and others ; a monoamine oxidase inhibitor maoi ; or beta-blockers tenormin and others .
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Sulonamids, including sulonamid-containing poducts such as BACTIM, should b discontinud at th ist appaanc skin ash any sign advs action. Clinical signs, such as ash, sthoat, v, athalgia, cough, shotnss bath, pallo, pupua jaundic may b aly indications sious actions. A skin ash may b ollowd by msv actions, such as Stvns-Johnson syndom, toxic pidmal ncolysis, hpatic ncosis sious blood disod. Complt blood counts should b don quntly in patints civing sulonamids. Cough, shotnss bath, and pulmonay iniltats a hypsnsitivity actions th spiatoy tact that hav bn potd in association with sulonamid tatmnt.
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Hmatologic changs indicativ olic acid dicincy may occu in ldly patints. Ths cts a vsibl by olinic acid thapy. Appopiat dosag adjustmnts should b mad patints with impaid kidny unction and duation us should b as shot as possibl tminimiz isks undsid actions [s DOSAG AND ADMINISTATION ].
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