Coadministration of sildenafil and indinavir is contraindicated for the treatment of pah.
Information about Indinavir.
In Phase I and II controlled trialsthe following adverse events were reported significantly more frequently by those randomized to the arms containing CRIXIVAN than by those randomized to nucleoside analoguesrashupper respiratory infectiondry skinpharyngitistaste perversion.
Cardiovascular Systemcardiovascular disorders including myocardial infarction and angina pectoriscerebrovascular disorder.
If you must take a drug that has the potential to interact with your existing medicationsyour doctor can do the following:
When HIV becomes resistant to one drug in a classit sometimes becomes resistant to other drugs in that classThis is called cross-resistanceFeel free to talk with your doctor about your current and future treatment optionsTo help you decide what these future therapies might beat some point your doctor can have a small sample of your blood analysed using resistance testingShould HIV in your body become resistant to indinavir your doctorwith the help of resistance testingcan help put together a new treatment regimen for you.
To reduce the risk of developing drug resistanceall anti-HIV drugs should be taken every day exactly as prescribed and directedIf doses are delayedmissedor not taken as prescribedlevels of indinavir in the blood may fall too lowIf this happensresistant virus can developIf you find you are having problems taking your medications as directedspeak to your doctor and nurse about thisThey can find ways to help you.
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