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You may have increased sexual urgesunusual urges to gambleor other intense urges while taking this medicineTalk with your doctor if this occurs.
Tell your doctor or pharmacist if you are using any of these medications beforeduringor within 2 weeks after treatment with selegilineTell your doctor or pharmacist if you have taken fluoxetine during at least 5 weeks before starting selegilineDiscuss with your doctor how much time to wait between starting or stopping any of these drugs and taking selegiline.
Because of the risk of hypertensionco-administration of selegiline and sympathomimetics is contraindicated.
Serious reactions with signs and symptoms that may include diaphoresisflushingataxiahyperthermiahyper/hypotensionseizurespalpitationdizziness and mental changes that include agitationconfusion and hallucinations progressing to delirium and coma have been reported in some patients receiving a combination of selegiline and fluoxetineSimilar experience has been reported in patients receiving selegiline order cystone tablet and two other serotonin reuptake inhibitorssertraline and paroxetineThere is a potential risk of interaction with fluvoxamine and venlafaxine.
Some studies concluded in an increased risk of mortality in patients receiving selegiline and levodopa compared to those receiving levodopa onlyHoweverit is noteworthy that multiple methodological bias were identified in these studies and that a meta analysis and large cohort studies concluded that there was no significant difference in mortality in patients treated with selegiline to those treated with comparators or with the association selegiline/levodopa.
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