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For Nausea/VomitingI went to the hospital due to a severe migraine and nauseaI was given compazine via I.VOh dearI immediately began having chattering teethsevere anxietyand uncontrollable clenching of teethI also could not remain stillas if I wanted to get out of there as fast as I couldI called the nurse in and the response was ohyeah you feel kinda outta of itWell yes it will pass don’t worryARE YOU SERIOUS RIGHT NOWIt’s just by the grace of God that I got home safelyMy teeth continued to chatterand could not sit stillI had to go back to the ER to get medicine to counter the side effectsI feel a little better nowDay 2 and still feel out of itI WILL NEVER TAKE compazine again
Acetylcholinesterase inhibitors may decrease the effectives of prochlorperazineCentrally acting acetylcholinesterase inhibitors may increase the neurotoxic effects of antipsychotic agentsCombining prochlorperazine with alcoholkava kavaCNS depressantsand cannabis may increase the risk of CNS depressant side effectsAntacids may decrease the absorption of prochlorperazineProchlorperazine may cause anticholinergic side effects such as dry mouthconstipationdry eyesdecreased urinary outputand mental confusionCombining agents with similar anticholinergic effects increases the risk of experiencing such adverse eventsProchlorperazine may increase the blood levels of dofetilideTikosynUse of both drugs is not recommendedDeferoxamineDesferalmay increase the risk of experiencing side effects of prochlorperazine treatmentCombination use has resulted in the prolonged loss of consciousnessMetoclopramideReglanmay increase the side effects of antipsychotic agentsCombination use is not recommendedProchlorperazine may increase the CNS depressant effects of orphenadrineNorflexor paraldehydeParalCombination use is not recommendedCombining prochlorperazine and potassium chloride may result in an increase in the ulcerogenic effect of potassium chlorideKlor-ConCombination use is generally not recommendedCombining prochlorperazine with thalidomideThalomidmay increase the risk of experiencing CNS depressant side effectsThis combination is generally not recommended.
For Nausea/VomitingI cannot believe all of these totally horrible experiences with compazineI was given in my IV for severe nausea and I had absolutely no side effects what so everI have taken another one now that I am home before I went to bedagain no problems or side effects at allHard to believe so many people are having such severe reactions
For Nausea/VomitingI was given compazine for extreme vomiting and it literally made me have an out of body experienceI could see my body in the hospital bed but it felt like I was getting up and waking away from the bed so I kept holding on to the railing of the bedIt was horribleI felt like I was two people and I had no control over my bodyI would never take this medicine again
Althoughthe exact mechanism of phenothiazine antipsychotics is unknownscientists believe that they may work by blocking the action of dopamine in the brainDopamine is a neurotransmitterchemicalthat nerves use to communicate with one anotherPhenothiazine antipsychotics are used when patients do not respond to other antipsychotics.
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