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The maintenance dosage required may range from less than 1 mg/kg bodyweight/day to 3 mg/kg bodyweight/daydepending on the clinical condition being treated and the individual patient responseincluding haematological tolerance.
Chronic immunosuppression with IMURANa purine antimetabolite increases risk of malignancy in humansReports of malignancy include post-transplant lymphoma and hepatosplenic T-cell lymphomaHSTCLin patients with inflammatory bowel diseasePhysicians using this drug should be very familiar with this risk as well as with the mutagenic potential to both men and women and with possible hematologic toxicitiesPhysicians should inform patients of the risk of malignancy with IMURANSee WARNINGS
To help prevent flare-upsyou can try to decrease the amount of fiber in your diet or avoid certain foods that are too spicybut most people with ulcerative colitis also need the help of drugsImuran is a medication that can help manage your symptoms of ulcerative colitisincluding stomach cramps and paindiarrheaand bloody stool.
Azathioprine suppresses disease manifestations as well as underlying pathology in animal models of autoimmune diseaseFor examplethe severity of adjuvant arthritis is reduced by azathioprine.
Symptoms of an allergic reaction usually happen within the first few weeks of treatmentThey include:
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