The active ingredient in zantac injection and zantac injection premixed is ranitidine hydrochloride hcl , a histamine h-receptor antagonist.

Some of the other drugs that glucovance interacts with include cimetidine, ranitidine, quinine, ciprofloxacin, trimethoprim, amiloride, procainamide, triamterene, isoniazid, niacin, synthroid, birth control pills, dilantin, diltiazem, diuretics, probenecid, and nonsteroidal anti-inflammatory drugs nsaids .