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Compounds of formula i include the following 2, 4, 7-triamino-6 pteridine, p-chlorobenzyl-triamterene ; 2, 4, 7-triamino-6 pteridine, p-fluorobenzyl-triamterene ; 2, 4, 7-triamino-6 pteridine, p-bromobenzyl-triamterene ; 2, 4, 7-triamino-6 pteridine, ; 2, 4, 7-triamino-6 pteridine, p-hydroxybenzyl-triamterene ; 2, 4, 7-triamino-6 pteridine, p-nitrobenzyl-triamterene ; 2, 4, 7-triamino-6 pteridine, p-aminobenzyl-triamterene and valtrex.